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B12/MIC is likely to be most effective when used as part of a healthy lifestyle, including a balanced diet and regular exercise

"And it's not because of any magic it's because these are natural substances that our bodies make and are familiar with, so that's what gives them this incredible safety profile." The FDA, however, has publicly stated that there is not enough evidence from human clinical trials on the safety or efficacy of these drugs

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However, supplementing solely with folic acid/folate can mask an underlying B12 deficiency