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Description

& Capelli, P

Ghanta SN, Kattamuri LPV, Odueke A, Mehta JL

GHK-Cu downregulates acute-phase and pro-inflammatory cytokines (TNF-?, IL-6), upregulates anti-oxidant defenses (including superoxide dismutase, Nrf2 and HO-1 pathways), and suppresses fibrotic signaling by inhibiting TGF-?1/Smad2/3 activation