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Ferroptosis is defined by excessive intracellular iron accumulation due to metabolic imbalance, where Fe 2+ generates a large amount of hydroxyl radicals (OH) through the Fenton reaction (Figure 2)

Styrene maleic acid-encapsulated RL71 micelles suppress tumor growth in a murine xenograft model of triple negative breast cancer

The fragment ion spectra of the S -mycothiolated Cys-peptides are characterized by diagnostic myoinositol-loss precursor ions (180 Da) that serve as markers for identification

In spinal cord injury, this peroxidation has been shown to precede mitochondrial dysfunction [83], while inhibition of lipid peroxidation with 21-aminosteroid in rats attenuated controlled cortical impact (CCI)-induced decreases in mitochondrial respiration [84]