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These sequencesfrom ferroptosis to inflammation mediated by released DAMPsexplain the ferroptosis arm of the vicious cycle

A tiny portion of the total iron is found to be Fe +2 as part of the labile iron pool (LIP), which can be used for biological purposes

Half-maximal inhibitory concentration (IC 50 ) was determined using the doseresponse inhibition model available in GraphPad Prism 9.0 (GraphPad Software, Inc., CA, USA)

Prediction analyses were performed through backward stepwise Cox proportional hazards regression and expressed as the hazard ratio (HR)

Most antirheumatic drugs exhibit a narrow therapeutic window, leading to side effects due to their specific distribution in the body

In this context, the following section highlights emerging evidence linking psoriatic inflammatory mediators, particularly Th17-associated cytokines, to neuroinflammation and neural plasticity