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If there is clinical improvement and if a reticulocyte response is observed, the same amount may be given on alternate days for seven doses, then every three to four days for another two to three weeks

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Overall, these studies highlight the complex role of PARPs and the impact of their inhibition in different pathological conditions

As a single agent or in combination with cisplatin: On Day 1 of each 21-day cycle, a dose of 500 mg/m2 of Alimta is recommended

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