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The major studies relating viral infection and glia cells have been developed in HIV-1 model infection

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Of note, GSTO1 was identified as one of the cellular targets of locostatin, an oxazolidinone-based cell migration inhibitor, although its role in cell migration has not been well characterized 42

The S1 subunit is further divided into an N-terminal domain (NTD) and a RBD (Fig

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While most intracellular glutathione is in a reduced state (GSH) with approximately 1% as an oxidized form (GSSG), this proportion can decrease in response to a variety of cellular stressors, including heavy metals, high glucose concentrations, poor nutrition, heat shock, reactive oxygen and nitrogen species, cigarette smoke, and other toxins including persistent organic pollutants