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NO-system & vasomotor tone: Concentration- and NO-dependent modulation of aortic vasomotion in ex vivo studies (Hsieh 2020)

10.1016/j.intimp.2020.106555 6 ArizaD.LimaM

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Mast cells are now thought to also play a pathogenic role in the condition.[ref] Researchers have found that the average prostaglandin D2 levels (an indicator of mast cell activation) are higher in people with rheumatoid arthritis than in healthy controls.[ref] Related article : Rheumatoid arthritis genes Mast cells may play a role in obesity and diabetes: It has been known for a while that obesity is linked to increased systemic inflammation

Investigation of the safety and efficacy of edaravone in 20 ALS patients who received this antioxidant intravenously indicated that this drug is safe and may delay the progression of functional motor disturbances by reducing OS (Yoshino and Kimura, 2006) (Table 1)