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Beyond conventional anti-inflammatory or anti-calcific agents, next-generation strategies could aim to correct the root metabolic derangements

Additionally, UA has demonstrated neuroprotective effects against oxidative stress caused by hydrogen peroxide (H2O2), thereby safeguarding neuronal survival in the face of elevated levels of reactive oxygen species (ROS) (Figure 5)

PMID: 29266896

Trends in cell biology

Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney

The researchers commented that the peptide suppressed caspase-dependent apoptosis that increases during aging of cell cultures