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Through ex vivo genetic modification, T cells are engineered to express chimeric antigen receptors, enabling them to recognize and eliminate cancer cells with enhanced specificity and efficacy

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The plasma concentrations of 13 C-labelled lactate and glutamine, although less than 10% of the unlabelled concentrations, could have contributed to some of the labelled lactate and, via glutamine, the labelled glutamate observed in the tumour sections (Extended Data Fig