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In those who developed psoriasiform dermatitis, topical therapy was required in 78% and systemic therapy (methotrexate or phototherapy) in 15.2%

10.1126/sciadv.aao0926 [DOI] [PMC free article] [PubMed] [Google Scholar] Foley N

Pharmaceuticals 12:17

Thus, age-related decreases in arginine availability which can be exacerbated by insulin resistance or malnutrition can limit NO-mediated perfusion of wounds and the vascularization of repair tissue (Table 3)