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Pharmacological inhibition of glutamine metabolism has been demonstrated in murine cancer models to limit glycolytic metabolism and oxidative phosphorylation in cancer cells, leading to hypoxia, acidosis, and decreased absorption of nutrients [47]

Asian J Psychiatry (2020) 51:102051

PBMCs and tumor tissues will be collected before and after treatment from both groups of mice

Synergism between metformin and analgesics/vitamin B12 in a model of painful diabetic neuropathy

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Fisher, B.J