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For thiol oxidations to be consequential inside cellsfor example, to inactivate an enzyme population to the extent that a pathway bottleneck arisesthe rate of thiol oxidation must be fast, with a majority of enzyme molecules being oxidized within a cell generation

However, given the vast number of different reactions taking place within the cell, this strategy is not feasible

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Arginine-modifying enzymes in pulmonary fibrosis Beyond its metabolic roles, arginine is subject to post-translational modifications, such as methylation and citrullination, which significantly impact pulmonary fibrosis

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