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The significance of the balance between whole-body proteins and amino acids is still unclear, especially in humans

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Metabolomic analyses have also revealed significant alterations in branched-chain AAs (BCAAs), including isoleucine, leucine, and valine, in serum and plasma of patients with IBD [22, 23, 26]

The self-assembled lipid vesicles have been extensively studied as a protocell model to decipher the emergence of compartmentalization and genetic polymer synthesis in the origin of life 8,9 , and its fatty acid or phospholipid bilayers are selectively permeable to solutes 9,10

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Lavoie H, Gagnon J, Therrien M (2020) ERK signalling: a master regulator of cell behaviour, life and fate