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Trigone as a diagnostic and therapeutic target for bladder-centric interstitial cystitis/bladder pain syndrome

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When administered by intravenous (IV) injections, the QMP-engineered albumin variant lacking L585 demonstrated enhanced cellular recycling and extended plasma half-life in transgenic mice expressing human FcRn, comparable to that of full-length QMP

Ros-Covin D, Ruas-Madiedo P, Margolles A, Gueimonde M, de Los Reyes-Gaviln CG, Salazar N

However, due to the small volume of the mouse brain, the ears and other structures exert greater interference on the brain tissue, causing serious artifacts, and may require higher resolution and field strengths for research

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