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The sensitivity of the assay was approximately 30 pg/ml

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Conversely, excessive ROS accumulation leads to DNA damage, induction of p53 and Fas ligand (FasL), and ultimately T cell apoptosis ( Figure 1 ), which can be advantageous in terms of controlling autoimmunity ( Figure 1 Given this finite balance, it is not surprising that ROS are generated by multiple pathways following TCR activation and, in parallel, eliminated by multiple antioxidant systems

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Vrije radicalen zijn instabiele moleculen die ontstaan door oxidatie en kunnen schade aanrichten aan je cellen