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Unexpectedly, the binding affinity of suramin to MARV polymerase was much lower than that to EBOV polymerase no matter under near-physiological (11.1 3.8 M) or high-salt conditions (17.3 3.1 M) (Fig

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Kiba-Janiak and Witkowski, 2019)

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neuropathy), effective replacement therapy should lead to a normal full blood count and B12 level after 8 weeks of treatment, while improvement in neurological symptoms begins very quickly within one week of initiation of therapy but can take up to 3 months to resolve (Carmel, 2008)

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