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Regular treatment and follow-up care can help ensure that vitamin B12 levels remain within a healthy range

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Patients must take Rybelsus on an empty stomach, upon waking, with no more than 4 ounces (120 mL) of plain water, and then must wait at least 30 minutes before eating, drinking other beverages, or taking other oral medications

This distinction is crucial for formulation stability, as it allows for versatile delivery methods (including oral bioavailability) that many fragile peptides cannot offer

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For the patient who likes fewer clinic visits and consistent drug levels, semaglutide is the easier choice