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Aging and age-related diseases Aging is a universal, intrinsic, irreversible, heterogeneous and multidimensional process of progressive involution characterized by a gradual loss of physiological functions that increases the probability of death

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Comprehensive preclinical safety evaluations across multiple animal models demonstrate favorable tolerability profiles with excellent safety margins for investigational research applications

Programs may start from a customer-supplied small molecule, an expected metabolite structure, or a labeled-handle concept, and can be aligned with broader amino acid conjugation, custom bioconjugation services, or thiol-reactive route planning informed by maleimide conjugation considerations when appropriate

Numerous ligands including HDL (187), LDL (188), selected polyanionic compounds of microorganisms (189), and - glucan recognized by SR (190)