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Exemplary antimicrobial preservatives include, but are not limited to, benzalkonium chloride, benzethonium chloride, benzyl alcohol, bronopol, cetyltrimethylammonium bromide (cetrimide), cetylpyridinium chloride, chlorhexidine (chlorohexidine), chlorobutanol, chlorocresol, chloroxylenol, cresol, ethanol, glycerol, hexetidine (hexetidine), imidurea, phenol, phenoxyethanol, phenylethyl alcohol, phenylmercuric nitrate, propylene glycol, and/or thimerosal (thimerosal)

doi: 10.1016/j.ajpath.2014.12.016

Because of the presence of an OH group on the chromanol ring of vitamin E, it is able to function as an antioxidant and reduces lipid peroxyl groups to hydroperoxides, thus terminating the propagation of lipid peroxidation [105,138]

Targeted therapies, including TNF- inhibitors and IL-6 receptor antagonists, effectively reduce inflammation and improve outcomes through cytokine blockade (Smolen, 2020)