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In mitochondrial dysfunctioning, a key issue is that of ROS

10.1207/S15327914NC402_12 80

1 Introduction Vitamins of the B complex comprise a group of eight water-soluble vitamins that play a crucial role in maintaining optimal neurological function, such as energy production, DNA/RNA synthesis/repair, genomic and non-genomic methylation, and synthesis of neurochemicals ( Figures 1 , 2 ) ( Figure 1 Figure 2 Thiamine (B1) deficiency is often associated with beriberi, a syndrome mainly characterized by polyneuritis and/or cardiovascular symptoms (24)

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