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It's also involved in 5 : Neutralizing singlet oxygen, hydroxyl radicals, and superoxide radials Serving a cofactor for antioxidant enzymes Regenerating vitamin C and E Neutralizing free radicals produced during Phase 1 liver metabolism of toxins Transporting mercury out of cells and the brain Regulating cell proliferation and apoptosis Supporting mitochondrial function Maintaining mitochondrial DNA Aside from its antioxidant role, one of the other key functions it's involved in is detoxifying both xenobiotic and endogenous compounds 5

The platelet adhesion to the injured diabetic endothelium takes part in ischemia and inflammation, both coagulation and fibrinolytic cascades in the vitreous are identified in DR 114

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However, the specific effects of ROS vary depending on their origin 61

Glaucoma: from pathogenic mechanisms to retinal glial cell response to damage