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Moreover, recent studies suggest that the induction of cellular senescence, rather than the promotion of apoptosis through radiotherapy or chemotherapy, might be the main mechanism for impairing the self-renewal capacity of cancer cells, particularly in the context of solid tumors [55]

2008;133(6):160S-198S

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In addition, Terreic acid simultaneously reduces the percentage of senescent cells and SASP expression in cells exposed to stress stimuli