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Aging and acute exercise enhance free radical generation in rat skeletal muscle

Remarkably, KDS12025 demonstrated significant efficacy in mitigating RA pathology, as evidenced by a reduction in the CIA score, a clinical measure of joint inflammation severity, and improvements in histological parameters, including synovial hyperplasia and cartilage destruction, as shown via H&E and toluidine blue staining (Supplementary Fig

Each of these RCD patterns is triggered and propagated through molecular pathways that exhibit significant connectivity (Tang et al., 2019) (Figure 2)

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