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Injectable hair protocol: Dose: 1-2mg daily Frequency: Daily or 5 days weekly Duration: 16-24 weeks minimum (longer than anti-aging protocols) Cycle: 8 weeks on, 4 weeks off, repeat Topical scalp protocol: Concentration: 0.5% solution Application: 1-2ml to thinning areas twice daily Duration: 6+ months for meaningful assessment Technique: Apply to clean, dry scalp

doi:10.1159/000053183 Wilding JPH, Batterham RL, Calanna S, et al

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Research Applications AOD-9604 is suitable for research programs where the investigator needs a clearly identified material and a focused scientific rationale

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These landmark studies showed that mice with adipose-tissue-specific NNMT knockout remained lean when fed high-fat diets that caused wild-type mice to become obese, and that these protected mice had increased energy expenditure, enhanced fatty acid oxidation, improved glucose tolerance, and elevated NAD+ levels in adipose tissue