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Perilipin A may also influence lipolysis by regulating the distribution and architecture of lipid droplets within adipocytes

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However, no research directly compares continuous use versus cycling protocols (such as 12 weeks on, 4-8 weeks off), leaving optimal long-term strategies somewhat uncertain

Furthermore, large-scale clinical trials are needed to evaluate the efficacy and safety of microbiome-targeted interventions, such as probiotics, prebiotics, dietary modulation, and fecal microbiota transplantation (104)

Kriss M, Hazleton KZ, Nusbacher NM, Martin CG, Lozupone CA (2018) Low diversity gut microbiota dysbiosis: drivers, functional implications and recovery