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Epithalon Research in Aged Rhesus Monkeys Non-human-primate findings are more biologically relevant than rodent results but remain preclinical

12, we provided the details on the inhibition rates of the reference drugs on these predicted target proteins

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NLRP3 inflammasome is a multimeric protein complex formed by the interaction of NLRP3 and apoptosis-associated speck-like protein containing (41), which enables caspase-1 activation and thus promotes the maturation and secretion of IL-18 and IL-1 (37)

doi: 10.1016/j.jconrel.2024.06.026 305 ZhaoLTanLWuQFuCRenXRenJet al

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