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Diagnosis can be made through hormonal and imaging tests, and treatment typically involves subcutaneous injections of synthetic GH replacement therapy to stimulate growth ( Sleep is an important period of increased GH release ( This narrative review (incorporating a systematic search of the literature) aimed to assess the relationship between GH and sleep in children, and assess the impact of GH therapy on sleep quality in children with idiopathic GHD ( Figure 1 )

Patients who focus on their nutrition and follow their healthcare providers advice on B12 supplements tend to do well long-term

Polycythemia vera An uncommon blood disorder where the red blood cell count increases too much

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Table 2 Comparative summary of clinical progress, translational opportunities, key challenges, and future directions of BBB-oriented therapeutic strategies for Alzheimer's disease