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This shows that the linker composition is essential to maintain functional O-GlcNAc homeostasis

[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Dabke P, Das AM

Evidence for glutamate dysregulation and excitotoxicity in different neurodegenerative diseases Excitotoxicity in acute diseases of the CNS As mentioned above, excitotoxicity was initially defined as an acute insult to nerve cells that leads to cell death by excessive activation of iGluRs

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This means that RONS can have stimulatory and inhibitory impact depending on the concentration

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