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Pharmacological Res

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Jakubowski H (2000b)

The study found that overexpression of WT BAP1 in UMRC6 cells hindered the cellular uptake of cystine, resulting in reduced GSH levels and increased erastin-induced lipid peroxidation [50]

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CRS, the most common non-hematologic adverse event observed after CAR T-cell therapy, is an escalated immune response and on rare occasions can evolve into a fulminant hemophagocytic lymphohistiocytosis (HLH)/macrophage activation syndrome (MAS)