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Notably, a polymorphism in the ABCC2 gene has also been suggested to lead to higher oxaliplatin concentration in neurons, and was associated with oxaliplatin induced neuropathy (Mori et al., 2008)

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Generation of transgenic mouse strains All animal studies and procedures were conducted according to a protocol approved by the Institutional Animal Care and use Committee (IACUC) at the Rockefeller University

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