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Mechanism of Action 5-Amino-1MQ has been investigated for its selective inhibition of nicotinamide N-methyltransferase (NNMT)

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Importance of neonatal FcR in regulating the serum half-life of therapeutic proteins containing the Fc domain of human IgG1: a comparative study of the affinity of monoclonal antibodies and Fc-fusion proteins to human neonatal FcR

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The half-life of AOD-9604 is 23 hours requiring once or twice-daily dosing, while 5-Amino-1MQ's enzyme inhibition persists 1824 hours allowing single daily administration

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