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The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations

S2CID 229393446

Think of it like a kinked fuel line

8 Subsequently, the anti-diabetic effect of flumamine which is today known as metformin was investigated in animals 9 and showed it had a powerful glucose-lowering effect which led investigators to suggest that because metformin appeared to be a glucose eater it should be called Glucophage and also reported that its precise mechanism of action remained relatively unknown, 10 an observation that is true today, despite many ensuing investigations

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While early research (mainly in gamers) is promising, more studies are needed, and nootropics aren't for everyone