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In contrast, iron overload induced significant downregulation of ACSL4 and GPX4 expression in these cells, suggesting a disruption in lipid homeostasis and a reduction in antioxidant defense mechanisms, which may contribute to the progression of iron-induced ferroptosis

S en una posicin que corresponde a la posicin 196 y S en una posicin que corresponde a la posicin 82

For studies with a calorie-restricted and body-weight-loss-matched control group, HFHS diet (58 kcal% fat, D12331i, Research Diets) was weighed and provided as one separate pellet per mouse at the time of injection

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The alignments can be global (alignment of sequences compared over the entire length of the sequences and including all the residues) or local (the alignment of a portion of the sequences that includes only the most similar region or regions or the like)

Available online: (accessed on Kashef, Z