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[2] in 2016 was the main interventional study on which the ADA has relied since 2017 to recommend regular monitoring of vitamin B12 levels in individuals treated with metformin, particularly in the presence of neuropathy or anemia [9]

Many people take high doses of standard vitamins only to have them pass through the system unused

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However, side effects like nausea, dizziness, or gastrointestinal discomfort may also become more likely as the dose increases

I was like, God damn it

Navigating microplastics and associated chemicals: a framework for personalized risk reduction [1:29:30]