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Results and discussion Previous work has shown that pyridinophane type molecules are low molecular weight entities that display potent antioxidant ability, low toxicity, and high metabolic stability in neuronal cell culture models, suggesting they could serve as potential agents to treat Alzheimers and other neurodegenerative diseases ( OH Py 2 N 2 pyridinophane (Figure 1) showed higher pharmacological efficacy and increased biological compatibility compared to the parent systems ( OH Py 2 N 2 could be utilized and as models to understand the mechanisms of this protective reactivity

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10.1016/S1369-5266(03)00039-6 23 LenA