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Ferroptosis is defined by iron-dependent lipid peroxidation, impaired GPX4 activity, and an expansion of the labile iron pool

These findings highlight the critical balance of GSH synthesis and cysteine redox state in regulating oxidative stress, fibroblast behavior, and fibrotic progression

doi: 10.1038/s41418-017-0012-4 32 ZhangKJWuQJiangSMDingLLiuCXXuMet al

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After completion of the reaction, the reaction mixture was poured into ice water, and the solid was obtained