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UGT1A1, UGT1A9, UGT1A6 and UGTB15 are reported to glucuronidate paracetamol

The identification of reduced cellular glutathione levels and deficient glutathione synthetase activity established this disorder as a unique entity

Initial column temperature was 90 C held for 1.5 min, increased to 220 C at a rate of 20 C min 1 , followed by a second ramp to 320 C at a rate of 10 C min 1 and held for 10 min