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More recently, Lucas et al

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Chelating agents help prevent metal ions from binding to other ingredients

It also induces the release of cytokines causing neuronal inflammation and defective endo-lysosomal trafficking (Pimplikar et al., 2010), altered intracellular signaling cascades, or impaired neurotransmitter release thereby contributing to synaptic dysfunction (Tang-Schomer et al., 2010)