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In vitro studies, Tan IIA (10 g/L) can inhibit ox-LDL-induced lipid deposition in RAW264.7 macrophages by inhibiting miR-214-3p/autophagy-related protein-16-like protein 1 (ATG16L1) pathway to promote autophagy (Qian et al., 2023)

Not surprisingly, the absence of a thick mucus layer in the Calu3 LLI model led to a higher transmigration rate for MC58 and 8013 strains compared to the ALI culture (Peters et al., 2024)

Similarly, other studies have found neurotransmitter dysregulation associated with mitochondrial disease in a subset of the ASD population [190]

However, over time, this theory has been increasingly revised as new findings emerged and newer models were proposed

Since the discovery of apoptosis, people have known that cell death is a programmed process that follows specific regulatory laws

(2019) 54(suppl 63):4274