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doi:10.1021/acs.chemrestox.8b00345

Neuron 65, 445459

Astorgues-Xerri, L

This clinical trial demonstrates that xanomeline has substantial effects in reducing behavioural and psychotic symptoms in patients with Alzheimers disease

Mutational analysis of conserved cysteine residues in the Fe/S domain of XPD indicated that an intact Fe/S domain is essential for helicase activity and/or stabilizing the protein structure (Liu et al., 2008