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Chem Soc Rev

Velez JC, Therapondos G, Juncos LA

The prevalence of impaired cerebral glucose metabolism suggests that KD may have beneficial effects by changing the major energy metabolism of the brain in SUD (Figure 2C)

These genes were subjected to GO enrichment/Molecular Function using the ShinyGO 0.82 platform

Despite these advances, KRAS inhibitors like sotorasib face resistance mechanisms primarily through the activation of bypass pathways such as autophagy and PI3K-AKT signaling