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The safety and efficacy of the promising therapies still need to be evaluated through a number of clinical trials with ethical support and fully informed consent

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Subsequently, the loss of neurons can spread to other SN pars compacta and other brain regions, including the ventral tegumental area, the locus coeruleus, the dorsal nucleus of the vagus nerve, and other neuromelanin (NM)-rich regions (Damier et al., 1999), of which NM is a ferric ion-protective chelating agent

J Biol Chem (2004) 279(35):3660815

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Those peptides were incubated with one stoichiometric equivalent with 100 M 13 C, 15 N-labeled FOXO4 FH