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1 Introduction Multiple myeloma (MM), a hematologic malignancy characterized by clonal proliferation of bone marrow plasma cells, manifests clinically through CRAB criteria: hypercalcemia, renal dysfunction, anemia, and osteolytic lesions ( Ferroptosis, an iron-dependent non-apoptotic cell death driven by excessive lipid peroxidation, was first characterized by Dixon et al., in 2012 through studies on erastin and RAS-selective lethal compounds (Zhang et al., 2022

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277 ZhangZ.ZhangY.YuwenT.HuoJ.ZhengE.ZhangW.et al (2022)

1 The Vd is the parameter used to assess the amount of drug in the body from the measurement of a snapshot plasma concentration

the multi-gene approach is more comprehensive but more complex

All U100 insulin syringes measure the same, but their size differences can make them look different