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Nutrition, metabolism, and epigenetics: Pathways of circadian reprogramming

Zhang W, Zou A, Miao J, Yin Y, Tian R, Pang Y et al

Chang, Yun-Hsuan, et al

In addition, ginsenoside Rg1 protects against renal fibrosis by regulating the Klotho/TGF-1/Smad signaling pathway (Sha-Sha et al., 2018)

doi: 10.1021/acs.jafc.6b02480 126

An increase in FAO causes increases in mitochondrial inner membrane potential and stimulates ROS 50,51 , which further causes oxidative damage of mitochondrial proteins and DNA, making them less efficient in energy metabolism