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Metabolic engineering of commensal bacteria for gut butyrate delivery and dissection of host-microbe interaction

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For example, IL-10 receptor mutations result in a severe, early onset colitis, which has been successfully treated by bone marrow transplant [115, 116]

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The two main metabolic functions of carnitine are to facilitate fatty acyl group transport into mitochondria and to maintain the ratio of acyl-CoA to free CoA in the mitochondria:[14] 1) Carnitine is an essential amino acid necessary for the beta-oxidation of fatty acids and energy production in mitochondria

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