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Endocrinology 157:en20151709

If you arent deficient, you may experience side effects taking a supplement

Longer than that and the fatigue and neuro symptoms start up again

Neurosci Lett 342:1316

Association between serum IGF-1 and diabetes among US adults

A 1994 in vivo study by Natera, Jiang, and Ng extended the observation into a whole animal, reporting that chronic administration of synthetic hGH 177 to 191 to genetically obese (ob/ob) mice was associated with reduced cumulative body-weight gain and reduced adipose mass relative to controls [2]