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Li Z, Huang K, Cao J, Guo M, Dong H, Ye W, Zeng S, Wei J, Xi Q (2025d) Silencing Hmox1 Attenuates Cerebral Ischemia/reperfusion Injury and Inhibits Inflammation and Ferroptosis Via the PPAR-/FABP4 Signaling Pathway

Additionally, many alkaloids trigger apoptosis in cancer cells by activating intrinsic pathways that promote the release of cytochrome c from mitochondria

Orrico et al., m aldehyde dehydrogenase 2 (ALDH2) virtually blocks the self-administration of ethanol (Karahanian et al., The logical extension that inhibiting the molecular mechanisms that initiate ethanol intake would also inhibit chronic alcohol intake proved to be wrong

p53 tumour-suppressor caution Because FOXO4-DRI intervenes in the p53 pathway, which is critical for tumour suppression, there is theoretical concern that interfering with p53 dynamics might carry oncogenic risk

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