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Pale or Jaundiced Skin: A lack of B12 may lead to anaemia, giving the skin a pale or slightly yellowish tone

[] Preferential OMA1 activation or YME1L suppression increases S-OPA1 levels, driving mitochondrial fragmentation

A comparison of our Sas Pcob structure with other photocobilin proteins (predicted structures obtained from the recently published Alphafold2 database 26 ), shows they can be divided into three main groups depending on the location of the AdoCbl-binding domain at either the N- or C-terminus, and whether they contain the additional output domain in the fused proteins (Supplementary Figs

They might experience mood changes, stiffness in the neck, fluid retention, and other symptoms