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It turns on local stem and progenitor cells that may help regeneration of ovarian and uterine tissues

To generate AdipoQ-CreERT2 x p53-Lox mice, female mice heterozygous for the CRE-transgene and homozygous for loxP-flanked allele were bred with male mice homozygous for loxP-flanked allele starting at the age of 10 weeks

At the end of the 56-d feeding, tissues (liver, intestine, skeletal muscle, kidneys, and pancreas) were collected for biochemical analyses

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Schlmerich et al ., Reference Schlmerich, Fellermann, Seibold, Rogler, Langhorst, Howaldt, Novacek, Petersen, Bachmann and Matthes2017