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Schmal H, et al

A: In vitro studies involve cells in a controlled environment, using molar concentrations (M), while in vivo studies involve whole organisms and use weight-based dosages (mg/kg)

Ursini and Maiorino, 2020

From predictive modeling to the design of MNP-based therapies, neurobiophysics continues to shape the future of neuroscience and its applications in treating neurological disorders

Most recently, AAV9-mediated SLC52A2 gene replacement normalized FMN/FAD levels, rescued spinal motor neurons and reversed motor deficits when delivered pre-symptomatically, underscoring the feasibility of curative therapy (19)

[26] The genes implicated vary in different ethnic groups, [27] and the impact of these genes on the disease differs significantly among people from different ethnic groups